LCD experience

[Thomas Meinert Larsen]

Hi All

We (UCPH) now have 4 LCD-groups of roughly 8 people going. Some have now followed the LCD for 4 weeks now.

We have some experience that some participants experience constipation. These symptoms can usually be relieved by asking participants to take some fiber tablets (in Denmark we have the brand "HUSK").

This is already described in the LCD SOP as a possibility, and now we just stress this again.

I am curious to know if you experience the same?

Our first LCD group are to finalize their 8 week LCD-period by 1 week of 2014, and then our first post-randomization group counselling starts :-)

/ Thomas

[Amy Liu]

Hi Thomas,

We (NZ) currently have our third cohort (around 45 per cohort) on the LED (week 4). We have found that some have reported constipation with more reports of loose bowels, esp in the first 1-2 weeks of starting the LED. As well as recommending the psyllium husk or metamucil, we have another product called benefibre which has both insoluble and soluble fibre to regular irregular bowel motions and have found this a success. For those with constipation we have also encouraged extra fluid intake.
Hope this helps :)

Amy